Clopidogrel may interact with other medications

• Diabetes drug. In most cases, repaglinide should not be taken with clopidogrel. ...
• Stomach acid drugs (proton pump inhibitors) ...
• Nonsteroidal anti-inflammatory drugs (NSAIDs) ...
• Blood thinners.
• Drugs used to treat depression. ...
• Salicylates (aspirin) ...
• Opioids.

What should you avoid with clopidogrel?

Cautions with other medicines

Some medicines affect the way clopidogrel works. Tell your doctor if you're taking any of these medicines before you start taking clopidogrel: medicines to prevent blood clots, such as aspirin, warfarin, rivaroxaban, apixaban, edoxaban, dabigatran, dipyridamole, ticagrelor or prasugrel.

Should clopidogrel be taken in the morning or evening?

You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.

When should you not take clopidogrel?

If you have certain health conditions such as a peptic ulcer or bleeding disorder you should not take clopidogrel, unless advised by a specialist. You should use clopidogrel with caution if you have liver or kidney problems. Clopidogrel must not be given to anyone under 16 years old, unless under specialist advice.

Can I drink coffee while taking clopidogrel?

These medications are used to slow blood clotting and include aspirin, clopidogrel (Plavix), ibuprofen (Advil, Motrin, and others), naproxen (Anaprox, Naprosyn, and others), enoxaparin (Lovenox), and more. Health experts advise caution when combining them with coffee, which can also slow blood clotting.

Clopidogrel Side Effects, Drug Interactions and Uses | Plavix Side Effects

Can you still have a stroke when taking clopidogrel?

The anti-blood clot regimen that adds the drug clopidogrel (Plavix) to aspirin treatment is unlikely to prevent recurrent strokes and may increase the risk of bleeding and death in patients with subcortical stroke according to late-breaking research presented at the American Stroke Association's International Stroke ...

Can you drink alcohol with clopidogrel?

️ Yes (within the recommended limits). Alcohol doesn't affect clopidogrel itself, but just be aware that drinking alcohol can irritate your stomach lining. This could increase the risk of getting a bleeding in the stomach.

What painkillers can I take with clopidogrel?

Painkillers. It's fine to take paracetamol with clopidogrel. You can also take opioid-type painkillers such as codeine, co-codamol, tramadol or morphine alongside clopidogrel.

Does clopidogrel affect sleep?

The organic nitrates (isosorbide) and the antiplatelet agents (acetylsalicylic acid, clopidogrel) are among the most prescribed drugs in cardiology and are not cited as causing insomnia or sleepiness.

Which is safer aspirin or clopidogrel?

Aspirin combined with the antiplatelet drug clopidogrel is no better than aspirin alone for stroke prevention in people with a history of lacunar strokes, and the combination carries a greater risk of gastrointestinal bleeding, according to results of a trial funded by the National Institutes of Health.

Can clopidogrel cause tiredness?

Clopidogrel may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away: excessive tiredness. headache.

How do you know if clopidogrel is working?

Talk to a pharmacist or your doctor before buying any over-the-counter medicine to check if it is compatible with clopidogrel. You may notice that you bruise or bleed more easily and it will take longer to stop bleeding while you are taking clopidogrel. This shows that clopidogrel is working.

Does clopidogrel cause joint pain?

Arthralgia and backache are also known to occur with its use. There have been case reports linking arthritis with the use of clopidogrel. We describe the case of a 64-year-old man who reported symptoms of fever and joint pains following initiation of therapy with clopidogrel.

What drug Drug Interactions is clopidogrel involved in?

Fluoxetine and norfluoxetine (the major active metabolite) block the formation of the active metabolite of clopidogrel by strongly inhibiting CYP2C19, CYP2C9, and CYP3A4, so potentially reduce the efficacy of clopidogrel, and there is also the possibility of a pharmacodynamic interaction.

Does clopidogrel interact with omeprazole?

FDA is recommending that the co-administration of clopidogrel (Plavix), a drug used to prevent blood clot formation, and omeprazole (Prilosec/Prilosec OTC), a proton pump inhibitor (PPI) used to reduce stomach acid, be avoided because omeprazole reduces the effectiveness of clopidogrel.

Can you take clopidogrel and amlodipine together?

Using amlodipine with clopidogrel can raise the risk for heart attack or stroke.

Does clopidogrel make you gain weight?

Weight changes, including weight loss, are not commonly seen with Plavix. However, Plavix has been shown to cause loss of taste in a few individuals within the first two to eight weeks of taking the medication. Patients who lose their sense of taste may also have decreased appetite, leading to weight loss.

Does clopidogrel cause leg cramps?

It frequently occurs in the legs and often causes claudication or pain in the legs upon walking. Plavix is used to reduce the risk of heart attacks and strokes in these patients.

Does clopidogrel cause shortness of breath?

Shortness of breath is not a common side effect of Plavix, but it may be symptom of a serious side effect of the drug. Plavix is used to help prevent blood clots from forming in your body. If you're taking Plavix, you were probably started on the drug because you had an increased risk of having blood clots.

What can I take for a headache while on blood thinners?

Safety of taking Tylenol with blood thinners

If you take blood thinners, such as Coumadin, Plavix, or Eliquis, your doctor may recommend taking Tylenol for pain as opposed to aspirin or ibuprofen.

Is it safe to take paracetamol with blood thinners?

Paracetamol isn't suitable for some people. Talk to your doctor if you take: the blood-thinner warfarin – paracetamol can increase the risk of bleeding if you take it regularly.

Can clopidogrel cause anxiety?

headache, fever, weakness, feeling tired; little or no urination; a seizure; low blood sugar--headache, hunger, sweating, irritability, dizziness, fast heart rate, and feeling anxious or shaky; or.

Can I take vitamin D with clopidogrel?

No interactions were found between clopidogrel and Vitamin D3.

Can you drink coffee while on blood thinners?

It was concluded that caffeine has the capacity to inhibit the metabolism of warfarin and enhance its plasma concentration and hence anticoagulant effects. Thus, patients should be advised to limit the frequent use of caffeine-rich products i.e. tea and coffee during warfarin therapy.

Can you drink orange juice while on blood thinners?

Grapefruit mostly impacts blood-thinning medications such as Apixaban (Eliquis), Rivaroxaban (Xarelto), Clopidogrel (Plavix) and Ticagrelor (Brilinta). If you're taking one of these medications and crave that citrus flavor, Dr. Crites suggests switching to orange juice.